Preventing Bacteria from Creating Resistance to Drugs Essay -- Explora

Preventing bacteria from Creating Resistance to DrugsIn 1943, the antibiotic drug era began when penicillin, a member of the beta-lacam family of drugs, was developed. Since then, tens of thousands of derivatives of penicillin have been developed, but only 17 antibiotics of this family are currently marketed in the United States. Penicillin and its derivatives work by preventing certain bacteria from skeletal frameing strong cadre walls that keep their shape and integrity. Without well-integrated cell walls, bacterial trying to grow in the presence of penicillin puff up and die.1 Almost all bacterial diseases have evolved some take aim of resistance. The increased use of antimicrobial drugs encourages the spread of resistance and increases the prevalence of drug-resistant strains.2 In fact, most virulent strains, like many sexually ancestral diseases, require at least double the dosage that was employ a decade ago. Vancomycin, commonly referred to as the last resort drug, is being used by hospitals in ever-increasing amounts.Bacterial resistance is the result of evolutionary responses. wholeness cause of resistance is through mutation. In some instances, proteins used to build the cell are altered to bind penicillin poorly or non at all. A second type of resistance occurs when the bacteria preemptively breaks checkmate penicillin into harmless by-products before they have the chance to bind with the cell wall. A greater cause for concern is the fact that bacteria may chuck with different bacterial species passing on resistance to bacteria that did non previously possess the ability to resist any drugs.3 Humans are the predominant cause for drug resistance. The following are some examples of how piece intervention has res... ...3. Palumbi. Pg. 81.4. Meanwhile, Back at the Farm in Infectious infirmity Alert. Nov. 1, 2001. vol. 21 i. 3 Pg. 17.5. Palumbi. Pg. 89.6. Palumbi. Reproduced from Table 4.1 on Pg. 75.7. Skolnic, Andrew. New Insight Into Ho w Bacteria Develop Antibiotic Resistance in The Journal of the American checkup Association. Jan. 2, 1991. vol. 265 n. 1. Pg. 14.8. For further reading consult Skurkovich, Simon. Facing the Coming Plague in gentlemans gentleman and I. June 1998. vol. 13 n. 6. Pg. 150.FURTHER READING & USEFUL LINKS1. This foundation was intended to be associated with the following articleEckert, Eric. Diseased Soieties in World and I. Oct. 1998. vol. 13 n. 10. Pg. 166.2. Lappe, Marc. Breakout The Evolving Threat of Drug-Resistant Disease. San Francisco Sierra Club Books, 1995.3. How Bacteria var. Resistance to Antibiotics presented by USA Today